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A Practical Approach to the Biochemical Assessment of Osteoporosis
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Chemical Pathology
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A Quick Guide to COVID-19 Tests
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Infectious Diseases
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Acquired Haemophilia A: Are We Missing the Diagnosis?
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Haematology
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Adult FBC Reference Intervals Explained
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Haematology
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An Approach to Autoimmune Encephalitis
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Immunology
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An Update on Autoimmune (Limbic) Encephalitis
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Immunology
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Anaemia of Chronic Disease (ACD) and Inflammation
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Haematology
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Anti-Müllerian Hormone (AMH): Physiology and Clinical Utility
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Chemical Pathology
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Antimicrobial Stewardship (AMS) in the Outpatient Setting
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Infectious Diseases
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Approach to the Neutropenic Patient
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Haematology
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Basic Approach to Abnormal FBC (Part 2): Platelets and White Blood Cells
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Haematology
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Basic Approach to Abnormal FBC: Part I (RBC Indices)
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Haematology
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Blood Safety: The Right Blood Product to the Right Patient at the Right Time
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Bordetella pertussis: Whooping Cough
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Breast Cancer: The Current Facts
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Histopathology
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COVID-19 Antibody Testing
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Infectious Diseases
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COVID-19 Antibody Tests: An Update
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Infectious Diseases
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COVID-19 T-Cell Responses
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Infectious Diseases
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CRP vs. PCT: Which One to Choose and When?
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Chemical Pathology
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Chromosomal microarray analysis in prenatal diagnostics
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Genetics
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Chronic Kidney Disease: Updated Recommendations on Definition and Classification
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Chemical Pathology
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Clinical Use of the D-Dimer Assay
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Haematology
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Cutaneous Manifestations of COVID-19
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Infectious Diseases
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Cystatin C: An Alternative Renal Function Marker
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Chemical Pathology
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Demystifying Cholinesterase Testing: Our Innovative In-House Solution to Biomonitoring
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Chemical Pathology
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Diagnosis and Investigation of Occupational Exposure to Metals
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Chemical Pathology
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Diagnosis of Thrombotic Thrombocytopenic Purpura (TTP)
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Haematology
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Drugs of Abuse Screening
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Chemical Pathology
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Familial hypercholesterolaemia detection
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Genetics
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Frozen Section: An Invaluable Tool for Intra-Operative Surgical Consultation
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Histopathology
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Genotype-Guided Antidepressant Prescribing
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Genetics
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HLA Tissue Typing: Introducing High-Resolution Typing with Next-Generation Sequencing (NGS)
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Genetics
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Haematopoietic Stem Cell Transplantation: An Overview
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Haematology
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Haemostasis Problems: A Logical Approach
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Haematology
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Helicobacter pylori: An Update
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Infectious Diseases
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Heparin-Induced Thrombocytopaenia (HIT): HIT Happens!
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Haematology
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Hypercalcaemia: A Diagnostic Approach
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Chemical Pathology
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Hypogonadism in the Elderly Male
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Chemical Pathology
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Improving Patient Care with Pharmacogenomic Testing
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Genetics
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Introducing the sFLT-1-PLGF ratio and its role in managing patients with pre-eclampsia MAY 2025
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Chemical Pathology
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Investigating Myeloid Neoplasms in the Era of Precision Oncology
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Genetics
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Investigating Solid Tumours in the Era of Precision Oncology
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Genetics
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Laboratory Markers for Alcohol Use
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Chemical Pathology
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Lipid Update: Changes to South African Dyslipidaemia Guidelines (2018) & New Markers for Assessing Lipid Status
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Chemical Pathology
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MPOX (Monkeypox) Disease
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Infectious Diseases
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Making Sense of the Laboratory Diagnosis of Asthma
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Immunology
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Molecular Pathology of Lung Cancer
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Histopathology
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Myelodysplastic Syndromes (MDS)
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Haematology
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Newborn Screening for Severe Primary Immunodeficiencies (TRECs and KRECs)
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Immunology
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Penicillin Allergy
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Immunology
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Pharmacogenomics: A Guide to a New Laboratory Test to Predict Drug Responses and Improve Patient Outcomes
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Genetics
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Pneumococcal Serotype-Specific Antibody Testing
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Infectious Diseases
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Post-Exposure Prophylaxis (PEP) After Occupational Exposure to HIV, HBV, and HCV
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Infectious Diseases
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Primary Hyperparathyroidism
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Chemical Pathology
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Primary Immunodeficiencies: A Diagnostic Approach
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Immunology
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Residual Cardiovascular Risk Factors
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Chemical Pathology
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Rubella Laboratory Diagnosis
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Infectious Diseases
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Safe at Work: Minimising Risk of New COVID-19 Infections in the Workplace
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Infectious Diseases
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Screening and Diagnosing Diabetes Mellitus During Pregnancy: Revised Criteria
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Chemical Pathology
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Screening and Diagnosis of Diabetes Mellitus Using Glucose Testing
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Chemical Pathology
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Screening for Inhalant Allergy in South Africa
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Immunology
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The ABC of HRD
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Genetics
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The Aetiology, Diagnosis, and Management of Vaginal Discharge Syndrome
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The COVID-19 Antigen Testing Solution
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Infectious Diseases
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The Case for Newborn Screening in South Africa: A Personal Perspective
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Chemical Pathology
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The Diagnosis of Vitamin B12 Deficiency Revisited
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Chemical Pathology
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The Diagnostic Approach to Coeliac Disease
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Immunology
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The Role of PFA-200 in Evaluating Platelet Dysfunction
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Haematology
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The Utility of the Urinary Lipoarabinomannan (U-LAM) Antigen in HIV-Infected Patients with Suspected Tuberculosis
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Infectious Diseases
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Three Extra Helpful Parameters on the Full Blood Count (FBC)
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Haematology
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Transfusion medicine
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Haematology
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Triple-Negative Breast Cancer (TNBC)
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Histopathology
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Update on the Management of Carbapenemase-Producing Enterobacteriaceae (CPE)
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Infectious Diseases
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Vitamin D Overview
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Chemical Pathology
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Antibiotic Guidelines
Guidelines to Antimicrobial Therapy and Laboratory Diagnosis of Infectious Diseases
Additional Resources
Allergy Guidelines Booklet
An allergy is a hypersensitivity reaction initiated by the immune system. Allergy can be antibody- or cell mediated. The antibody typically responsible for an allergic reaction belongs to the IgE isotype, and these individuals may be referred to as suffering from an IgE-mediated allergy. Individuals suffering from a cell-mediated allergy are referred to as suffering from a non-IgE mediated allergy.
Reactions not initiated by the immune system are not allergy and cannot be detected by allergy tests. Examples of these are lactose intolerance, sensitivity to caffeine and other intolerances.
