Lab Updates

New Oncology Genetic Testing for Solid Tumours (OCAPLUS)

Lab Updates
New Oncology Genetic Testing for Solid Tumours (OCAPLUS)
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Introducing OCAPLUS

Ampath is proud to launch the Oncomine™ Comprehensive Assay Plus (OCAPLUS) – the most comprehensive solid tumour genetic profiling currently available in South Africa.

Key Features:
  • 500 key cancer genes sequenced
  • Includes analysis for:
    • Tumour Mutational Burden (TMB)
    • Microsatellite Instability (MSI)
    • Homologous Recombination Deficiency (HRD)

OCAPLUS uses Ion Torrent Next Generation Sequencing (NGS) technology, allowing simultaneous detection of targetable variants across a wide range of solid tumours.

TMB can also be requested as a stand-alone test.

Why Choose OCAPLUS?
  • Offers greater genetic coverage than any previous Ampath panel
  • Cost-effective alternative to ordering multiple individual tests
  • Enables precision oncology with actionable genomic insights
Comparing Key Solid Tumour Assays at Ampath
OCAPLUS (Oncomine™ Comprehensive Assay Plus)
  • Genes sequenced: ~500 (including 49 fusion genes)
  • Detects:
    • Gene fusions
    • Copy number variants
    • Genomic instability (LOH/HRD)
    • Tumour mutational burden (TMB)
    • Microsatellite instability (MSI/MMR)
  • Turnaround time: 10–14 working days
  • Specimen: Tumour tissue
  • Mnemonic: OCAPLUS
  • Billing codes: 4763 × 1, 4765 × 24
OPANGS (Oncomine™ Precision Assay – DNA only)
  • Genes sequenced: ~50 (including 18 fusion genes)
  • Detects gene fusions and CNVs
  • Turnaround time: 7 working days
  • Specimen: Tumour tissue or liquid biopsy
  • Mnemonic: OPANGS
  • Billing codes: 4763 × 1, 4765 × 10
EGFRRASSEQ
  • Genes sequenced: ~50
  • Focused panel for specific mutations
  • Turnaround time: 7 working days
  • Specimen: Tumour tissue or liquid biopsy
  • Mnemonic: EGFRRASSEQ
  • Billing codes: 4763 × 1, 4765 × 4
For More Information

Contact the NGS Laboratory:
Tel: 012 678 0645
Email: ngs@ampath.co.za